KITP program on                                  Memory Formation in Matter                  Santa Barbara, 11 January 2018

Immunological Memory & Immunological Tolerance

Summary

I.       Introduction: T-cells, receptors, thymic selection                                                    

II.      Model: Model & Analysis: binding, positive and negative selection, Exterme Value Distribution, exact enrichment factors           

III.      Results and experiments: specificity and self-reactivity, amino-acid bias, contact profiles      

IV.      Quorum sensing      

V.       Learning from examples: boradly neutralizing Antibodies

Andrej Kosmrlj, Hanrong Chen

Tom Butler, John Barton, Assaf Amitai, Shenshen Wang

Abhishek Jha, Eugene Shakhnovich, Eric Huseby, Arup K. Chakraborty

Next (Introduction) Outline Introduction Model Results Quorum sensing Summary